Sertraline reduced patient dropout rates and acute exacerbation of symptoms in obsessive compulsive disorder

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منابع مشابه

Sertraline reduced patient dropout rates and acute exacerbation of symptoms in obsessive compulsive disorder.

Main outcome measures Dropout from the study because of relapse or insufficient response, acute exacerbation of OCD symptoms, relapse, and quality of life. Relapse was defined according to 3 criteria: increase in Yale Brown Obsessive Compulsive Scale (YBOCS) score of ≥ 5, total YBOCS score of ≥ 20, and ≥ 1 point increase on the Clinical Global Impression (CGI) improvement scale during 3 consecu...

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Sertraline in the treatment of obsessive-compulsive disorder.

S everal lines of investigation support a serotonergic hypothesis for the pathophysiology and treatment of OCD. Clomipramine, a tricyclic antidepressant that is a potent serotonin uptake inhibitor, was the first pharmacologic treatment for OCD to be studied in large multicenter trials. The successful outcome of these studies resulted in marketing approval by the United States Food and Drug Admi...

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Effects of Family and Patient Oriented Educational Program on the Symptoms of Patients with Obsessive-Compulsive Disorder

Background and purpose: Obsessive compulsive disorder (OCD) has negative impacts on patients and their families. This research was conducted to determine the effect of family and patient oriented education program on obsessive-compulsive symptoms in patients with OCD. Materials and methods: This semi-experimental study was carried out in 50 patients and their primary caregivers in Sari, Iran 2...

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The role of alexithymia and irrational beliefs in predicting obsessive-compulsive disorder in people with obsessive-compulsive disorder

The present study aimed to predict obsessive-compulsive disorder based on alexithymia and irrational beliefs in people with obsessive-compulsive disorder. The present study is a descriptive correlation. The statistical population included all patients referred to Imam Hossein Hospital in Karaj in the quarter (October, November, and December) of 2020, which was selected by the available sampling...

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Patient-reported outcomes in obsessive-compulsive disorder

The purpose of the article was to provide an overview of patient-reported outcomes (PROs) and related measures that have been examined in the context of obsessive-compulsive disorder (OCD). The current review focused on patient-reported outcome measures (PROMs) that evaluated three broad outcome domains: functioning, health-related quality of life (HRQoL), and OCD-related symptoms. The present ...

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ژورنال

عنوان ژورنال: Evidence-Based Mental Health

سال: 2002

ISSN: 1362-0347

DOI: 10.1136/ebmh.5.4.115